Whole-genome SNP-based phylogenetic analysis of Yersinia pestis isolates from Georgia and neighboring Caucasian countries
نویسندگان
چکیده
منابع مشابه
Different Region Analysis for Genotyping Yersinia pestis Isolates from China
BACKGROUND DFR (different region) analysis has been developed for typing Yesinia pestis in our previous study, and in this study, we extended this method by using 23 DFRs to investigate 909 Chinese Y. pestis strains for validating DFR-based genotyping method and better understanding adaptive microevolution of Y. pestis. METHODOLOGY/PRINCIPAL FINDINGS On the basis of PCR and Bionumerics data a...
متن کاملA North American Yersinia pestis Draft Genome Sequence: SNPs and Phylogenetic Analysis
BACKGROUND Yersinia pestis, the causative agent of plague, is responsible for some of the greatest epidemic scourges of mankind. It is widespread in the western United States, although it has only been present there for just over 100 years. As a result, there has been very little time for diversity to accumulate in this region. Much of the diversity that has been detected among North American i...
متن کاملInsights into the evolution of Yersinia pestis through whole-genome comparison with Yersinia pseudotuberculosis.
Yersinia pestis, the causative agent of plague, is a highly uniform clone that diverged recently from the enteric pathogen Yersinia pseudotuberculosis. Despite their close genetic relationship, they differ radically in their pathogenicity and transmission. Here, we report the complete genomic sequence of Y. pseudotuberculosis IP32953 and its use for detailed genome comparisons with available Y....
متن کاملYersinia pestis Evolution on a Small Timescale: Comparison of Whole Genome Sequences from North America
BACKGROUND Yersinia pestis, the etiologic agent of plague, was responsible for several devastating epidemics throughout history and is currently of global importance to current public heath and biodefense efforts. Y. pestis is widespread in the Western United States. Because Y. pestis was first introduced to this region just over 100 years ago, there has been little time for genetic diversity t...
متن کاملGenome sequence of Yersinia pestis KIM.
We present the complete genome sequence of Yersinia pestis KIM, the etiologic agent of bubonic and pneumonic plague. The strain KIM, biovar Mediaevalis, is associated with the second pandemic, including the Black Death. The 4.6-Mb genome encodes 4,198 open reading frames (ORFs). The origin, terminus, and most genes encoding DNA replication proteins are similar to those of Escherichia coli K-12....
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: International Journal of Infectious Diseases
سال: 2019
ISSN: 1201-9712
DOI: 10.1016/j.ijid.2018.11.203